In a recent University of Missouri Columbia study on rats, regular exercuse ket weight down, but after 2 days without exercise, the rats fat cells were 19 percent larger and the fat around their stomach increased by 25 percent. Yuck. We don’t need more studies on humans to get the point! Results fade fast if you don’t exercise regularly. As if that weren’t enough, the study also showed that inactivity led the body to use insulin poorly, increasing risk of diabetes and other related diseases.